Our results showed that miR-335 was downregulated in either NSCLC tissues or cell lines comparing to the Control group (Figure 6A, 6B), which was negatively correlated with LncRNA-XIST and SOD2 (Figure 6C, 6D) and in line with the Pan-cancer analysis in lung adenocarcinoma (Figure 6E, 6F). This evidence concerns the gene SOD2 and lung adenocarcinoma.