Paralleling these zebrafish model studies, non‐diabetic human carriers of the hyperglycemia risk allele within the FOXN3 locus show blunted suppression of glucagon during an oral glucose tolerance test, while showing no differences in fasting glucagon; except for fasting glucose, these FOXN3 hyperglycemia risk allele carriers do not have different glucose or insulin parameters during the oral glucose challenge (Karanth et al., 2018). The gene discussed is INS; the disease is Hyperglycemia.