Recently, a polygenic risk score for AF was constructed with four genetic variants, rs1448818, rs2200733, rs6843082, and rs6838973, from the PITX2 locus and one from the ZFHX3 locus, rs2106261, to predict AF recurrence after ablation in another Korean population (134) from the Seoul National University Hospital and Korea University Guro Hospital. The gene discussed is ZFHX3; the disease is atrial fibrillation.