ICAM1 and familial pancreatic carcinoma: Another study showed that the activity of intercellular adhesion molecule-1 (ICAM-1), VEGF, and MMP-9, the downstream transcription target genes of NF-κB (34–36), were stifled owing to NM-induced suppression of NF-κB activity, inhibiting pancreatic cancer cell adhesion, anoikis, and invasion (13).