To rule out a possible effect of IL6 signaling on blood lipid level, a causal risk factor for CAD, genetic association data on plasma lipid levels were assembled for MR analysis with individual data from UKB: high-density lipoprotein (HDL, n = 255,929), low-density lipoprotein (LDL, n = 279,367), total cholesterol (n = 279,913) and triglycerides (n = 279,686). This evidence concerns the gene IL6 and coronary artery disorder.