The corresponding gene MAP3K7CL is overexpressed in arteries, including coronary arteries and the aorta, and associated with coronary artery disease (Miller et al., 2016), and a recent genome-wide association study (GWAS) for heart failure suggests it is the top risk gene for coronary artery disease (Aragam et al., 2018). The gene discussed is MAP3K7CL; the disease is heart failure.