PDCD4 and peripheral T-cell lymphoma, not otherwise specified: STAT5 is a member of the STAT family of transcription factors, the activation of which has been shown to be essential in peripheral T-cell lymphomas, promoting it as a possible therapeutic target (Simpson et al., 2018), Although PDCD4 is generally considered as a tumor suppressor, however, pro-inflammatory roles have been suggested for it as well (Young et al., 2010).