CD68 and hepatocellular carcinoma: Notably, high CD68+ macrophage density was associated with reduced OS (HR = 3.12; 95% CI 1.34–7.27; P = 0.0085) and DFS (HR = 4.44; 95% CI 1.92–10.26; P = 0.0005) in HCC patients (Figures 2C,D, respectively).