Median of maximum CRP was significantly lower in mild, 95.18 (IQR: 28.73–175.53) mg/l and in moderately severe 213.20 (IQR: 119.20–292.00) mg/l, than in severe AP 232.90 (IQR: 147.50–333.95) mg/l (mild vs. moderately severe AP, p < 0.001; mild vs. severe AP, P < 0.001; moderately severe vs. severe AP, P = 0.729) (Figure 4A). The gene discussed is CRP; the disease is alkaline phosphatase measurement.