APOE and hypertensive disorder: As recently reviewed by the Society for Women’s Health Research Interdisciplinary Network on AD, these could be represented by: (1) genetic factors that have a stronger effect in women [i.e., apolipoprotein E (APOE) genotype]; (2) risk factors that differentially affect men and women (i.e., hypertension); or (3) biological events that are uniquely experienced by women (i.e., menopause, pregnancy; Nebel et al., 2018).