The genes we chose for AD were APP (Amyloid Beta Precursor Protein); Tau/MAPT; PSEN1 (Presenilin 1), PSEN2 (Presenilin 2), APOE (Apolipoprotein E), and GSK3B (Glycogen Synthase Kinase 3 Beta). This evidence concerns the gene PSEN2 and Alzheimer disease.