With maturation of the iPSCs technology, the establishment of an iPSCs cell model from a LRRK2:G2019S PD patient was reported in 2011 (Nguyen et al., 2011), and related publications have gradually increased (Liu et al., 2012; Mak et al., 2012; Reinhardt et al., 2013; Schwab and Ebert, 2015). Here, LRRK2 is linked to Parkinson disease.