CD44 and scrapie: For example, in prion agent strain/recipient mouse genotype combinations that displayed diffuse PrPd accumulation e.g., ME7, experimental sheep scrapie 22A, 22C, 22F, and 22L and experimental goat scrapie derived strains 79A, 79V, 80A and 139A, the abundance of the CD44 expression was similarly diffuse (Figures 3B,C,E, 8B,C,E).