RHO and autosomal dominant retinitis pigmentosa: Indeed, CRISPR/Cas9 constructs were also successfully delivered by electroporation in photoreceptor cells to target and disrupt by NHEJ the rhodopsin mutated allele in heterozygous P23H mice (Latella et al., 2016; Giannelli et al., 2018) and in S334ter rats, both model of autosomal dominant retinitis pigmentosa (Bakondi et al., 2016).