In this context, mitochondrial network morphology has been of interest in PRKN-PD fibroblasts studies but with controversial results (Mortiboys et al., 2008; Grunewald et al., 2010; Pacelli et al., 2011; van der Merwe et al., 2014; Zanellati et al., 2015; Haylett et al., 2016). This evidence concerns the gene PRKN and Parkinson disease.