The prognostic predictive accuracy of (PSA + miR-342-3p + miR-374b-5p) panel to discriminate between a group of men with GS ≥ 7 and a group of men presenting moderate PSA levels without cancer or with GS6, is also shown and indicates that it has a clinically useful prognostic potential (Sn: 81,8% and Sp: 95%). The gene discussed is KLK3; the disease is cancer.