In the same study, they also identified a previously unreported NTRK2 fusion (ETV6–NTRK2) in a 77-year-old male with AML and studied its transforming potential and downstream signaling in a cytokine-dependent murine hematopoietic cell line (Ba/F3 cells) and in a patient-derived xenograft model [66] (Fig. 2a). Here, NTRK2 is linked to acute myeloid leukemia.