TP53 and Parkinson disease: Finally, significantly enriched (adjusted p-value < 0.001) PANTHER29 pathways for the miRNA-based network nodes indicated the nodes in the network were part of the potential pathways associated with PD, including p53 signaling pathways, TGF-β signaling pathway, oxidative stress response, and immunological pathways such as the response to interleukin and interferon-gamma signaling pathway (Fig. 5D).