We found that the CER (d18:1/24:1) decreasing variant SPTLC3 rs364585-G was associated with decreased risk of intracerebral haemorrhage, while CER (d18:1/24:0) increasing variant ZNF385D rs13070110-C was nominally associated with increased risk of intracerebral haemorrhage. The gene discussed is ZNF385D; the disease is intracerebral hemorrhage.