These include the melanoma growth stimulatory activity, interleukin-8, regulated upon activation normal T-expressed, monocyte chemotactic protein-1, neutrophil activating protein 2 and 3, epithelial neutrophil activating peptide-78, angiogenesis-related platelet factor 1, and growth-related gene alpha [5, 6]. This evidence concerns the gene CXCL8 and melanoma.