It also increased the expression of the inhibitor IKBα (p = 0.0228) and the antiviral gene CAMP (p = 0.0007) that has one VDRE at its promoter region, but not EDN (p = 0.0597) or SLPI (p = 0.0697) before HIV-1 infection (Fig 4A). This evidence concerns the gene RNASE2 and HIV-1 infection.