As TNFAIP6 showed the highest genetic alterations among the top three genes in TD-expressing cells, we focused on the function of TNFAIP6. To investigate whether TNFAIP6 could trigger the metastatic properties of NSCLC, active PLK1-expressing cells were treated with shRNA for TNFAIP6 (Fig. 6c, d). Here, TNFAIP6 is linked to non-small cell lung carcinoma.