BRAF mutations were exclusively found in tumors from the proximal colon (40.0% vs 0.0%, P < 0.001), as well as mutations in the EGFR, JAK1, MAP2K4, MAP3K1, NBN, ALK genes (each of these mutated in 2 tumors), and BRCA1, BRIP1, CREBBP, FLT3, FLT4, MLH1, MPL and NT5C2 genes (each of these mutated in 1 tumor). This evidence concerns the gene FLT4 and neoplasm.