Expected inverse relationship during the early Foc TR4 infection stage was identified between mac-nmiR21 and CUP, and mac-miR397b.2 and LAC. However, no contrasting expression pattern was found between the expression of the other miRNAs and their corresponding target genes, indicating that they may not target genes or these genes’ expression regulation were more complex22. The gene discussed is LCT; the disease is infection.