Thereafter, CD146 has been shown to be expressed in various cancers, such as pancreatic, breast, prostate, ovarian, lung, kidney cancers, osteosarcoma, Kaposi sarcoma, angiosarcoma, Schwann cell tumors, children and adult acute B cell lymphoblastic leukemia, or leiomyosarcoma [30]. The gene discussed is MCAM; the disease is cancer.