Two of the three down-regulated genes are uncharacterized—AC013268.5 (ENSG00000283684) and RP11-192H23.6 (ENSG00000265287.2), whereas ANO7 is an androgen-responsive gene associated with prostate cancer (Fig. 6D; Bera et al. 2004; Pedemonte and Galietta 2014). Here, ENSG00000280371 is linked to prostate cancer.