In T-cytotoxic (CD8+) (Tcyt) cells, an initial decline was observed in the percentage of the cells from 0.7 to 0.07% of total live cells at day 1 of NTHi infection, which gradually increased to around 1% at days 5, 6, and 7 of NTHi infection (Table 4). The gene discussed is CD8A; the disease is infection.