Brass and coworkers have confirmed these findings through a detailed flow cytometric analysis of CD123 in a very large set of AMLs, showing that CD123 was expressed in the large majority of AMLs, with low expression in erythroid and megakaryocytic leukemia, higher CD123 expression in FLT3-ITD-mutated and NPM1-mutated AMLs [57]. The gene discussed is IL3RA; the disease is acute megakaryoblastic leukemia.