CDH2 and hepatocellular carcinoma: Cui et al. [43] analysed its effects on hepatocellular carcinoma cells and found the suppression of proliferation, migration, and invasion, as well as downregulation of the mesenchymal genes TWIST, SNAIL, N-CADHERIN, and VIMENTIN. Zanetti et al. [44] also found that ATRA induces epithelial differentiation program in breast tumour cells.