Additionally, we reported a GH-induced upregulation and GHRKD-induced suppression of MITF-regulated melanogenesis pathway genes—TYR, TYRP1, TYRP2/DCT—as well as melanosomal markers PMEL (gp100) and MLANA, in multiple melanoma cell lines, xenograft models, and in silico analyses. The gene discussed is TYRP1; the disease is melanoma.