Global gene expression analysis has demonstrated that genes such as insulin-like growth factor 2 (IGF-2), delta-like 1 homolog (DLK1), transforming growth factor beta 1 (TGF beta-1), mitogen-inducible gene 6 (MIG-6), and non-coding RNA MALAT1 are induced in HB but not in HCC [11]. The gene discussed is IGF2; the disease is hepatocellular carcinoma.