Using TCGA datasets of fibroblastic sarcoma, glioblastoma and triple negative breast cancer patient cohorts, we observed no significant correlation between gene expression of ATX and that of most of the eight hypoxia-regulated genes in the fibroblastic sarcoma and glioblastoma cohorts, while there was an overall negative correlation in breast cancer patients (Figure 2A–C). The gene discussed is ENPP2; the disease is breast cancer.