Representative luminescence figures of TC-1/LG tumor cells co-cultured with E7-specific CD8+ cytotoxic T cells with or without anti-PD-L1 Ab are shown in Figure 2D. The E7-specific CD8+ cytotoxic T cells treated with anti-PD-L1 Ab (8.5 ± 0.5 × 107 p/s) had significantly less luminescence than those treated with isotype Ab (1.5 × 108 ± 2.8 × 106 p/s, p < 0.001, Student’s t-test; Figure 2E). Here, CD274 is linked to neoplasm.