Similarly, immune-mediated host inflammation after infestation by Sarcoptes scabiei is also found in scabies [6,15,16,17,18], along with elevated levels of interleukin (IL)-4 and IL-6 [6,14,18], the latter of which is an upstream inflammatory cytokine that has been found to play a key role in both atherosclerosis and coronary heart disease [19,20]. The gene discussed is IL4; the disease is atherosclerosis.