HMCES and Flavivirus Infections: Among these, proteins earlier involved in PPI or associated with flavivirus replication were consistently identified (e.g., PAF1 and multiple hnRNPs), as well as novel host factors previously not associated with flavivirus infections (e.g., RBMX, RNA-binding motif protein X chromosome; NONO, non-POU domain-containing octamer-binding protein; and HMCES, embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein).