For a suitable simulation of a representative environment, e.g. an MS relapse during the treatment with DMF, we pre-treated the cells with DMF or MMF for 24 h and then stimulated them with the cytokines IFN-γ (50 ng/mL) and IL-1β (10 ng/mL) for different periods of time (3, 12, 24, and 48 h). This evidence concerns the gene IL1B and myeloid sarcoma.