At 5 days post-ischemia, mTOR and p-mTOR immunoreactivity was significantly decreased (about 22%, p < 0.001, and 19%, p < 0.001 of the HFD sham group, respectively) due to 2-min TI-induced death of CA1 pyramidal cells (Figure 8A-a8,8B-b8,C,D). This evidence concerns the gene MTOR and ischemia.