MTOR and ischemia: In the ND 2-min TI group, mTOR and p-mTOR immunoreactivity was significantly increased (about 129%, p < 0.05, and 125%, p < 0.05 of the ND sham group, respectively) at 2 days post-ischemia, and the increased immunoreactivity sustained until 5 days post-ischemia (Figure 8A-a4,8A-a7,8B-b4,8B-b7,C,D).