In the ND 2-min TI group, Iba-1+ microglia showed larger cell bodies with stouter processes, and the ROD of Iba-1+ structures was significantly increased (about 130%, p < 0.05, and 138%, p < 0.01 of the ND sham group, respectively) at 2 and 5 days post-ischemia (Figure 6A-a4,6A-a7,B). Here, AIF1 is linked to ischemia.