In the HFD 2-min TI group, no significant change in NeuN+ and F-J B+ CA1 pyramidal cells was observed at 2 days post-ischemia (Figure 4A-a5,4A-a5′,B,C): however, at 5 days post-ischemia, a significant decrease of NeuN+ CA1 pyramidal cells (7 cells/250 × 250 μm, p < 0.001) and a significant increase of F-J B+ CA1 pyramidal cells (66 cells/250 × 250 μm, p < 0.001) were both observed compared to those in the ND 2-min TI group (Figure 4A-a8,4A-a8′,B,C). Here, RBFOX3 is linked to ischemia.