Fibrosis is a complex process orchestrated by the production and release of pro-inflammatory and/or pro-fibrotic cytokines such as TNF-α, transforming growth factor (TGF)-β (but frequently anti-inflammatory), platelet-derived growth factor (PDFG), IL-1β, and IL-17 as well as those anti-fibrotic cytokines which might counterbalance the final result such as IL-10, IL-22, IL-6, and IFN-β/γ (IL-6 and IFN-γ are generally pro-inflammatory) [177]. The gene discussed is IL6; the disease is fibrosis.