Downregulation of SCGB3A2 (lung surfactant) and TPPP3 (bind tubulin and microtubulin) which are collectively involved in maintaining cell macrostructure and overall tissue integrity is also noteworthy; perhaps aiding the growth, proliferation or dissemination of the bacteria within the lung and the circulatory system, beyond the primary foci of infection. Here, TPPP3 is linked to infection.