Consistent with the current results, previous observations noted that EphA2 signaling protects breast cancer cells from death (Harada et al., 2011), EphB3 signaling suppresses Fas‐induced apoptosis in T cells (Maddigan et al., 2011), and the kinase inhibitor AZ12672857 reduces the viability of selected colorectal carcinoma cells (McCall et al., 2016). This evidence concerns the gene EPHB3 and colorectal carcinoma.