Consistent with the current results, previous observations noted that EphA2 signaling protects breast cancer cells from death (Harada et al., 2011), EphB3 signaling suppresses Fas‐induced apoptosis in T cells (Maddigan et al., 2011), and the kinase inhibitor AZ12672857 reduces the viability of selected colorectal carcinoma cells (McCall et al., 2016). Here, EPHB3 is linked to breast cancer.