This is likely attributable to the expression of Eph tyrosine kinase receptors that are not EphrinB2 receptors (Kania and Klein, 2016) in colorectal carcinoma cells (Herath et al., 2012) and to the broad Eph targeting of the TKI NVP (Martiny‐Baron et al., 2010). This evidence concerns the gene EPHA1 and colorectal carcinoma.