We performed genome‐wide mRNA expression profiling of the DLD‐1 wt and DLD‐1 G13D cell lines (Table 1 and Fig. 1) and, from the limited number of differentially expressed genes between the two cell lines, identified two, c‐Kit and TRIM59, that could conceivably play a role in the effects of TIMP‐1 on CRC cells. This evidence concerns the gene TRIM59 and colorectal carcinoma.