IL2 and neoplasm: Philogen (Switzerland) are developing a number of immunocytokines for oncology indications including Fibromun, a scFv (L19) against the tumour antigen EDB fused to TNF, Darleukin, which contains L19 scFv fused to IL-2, Teleukin, which contains a vascular targeting antibody F16 linked to IL-2, and Dodekin which contains two subunits of the immunomodulatory payload IL-12 fused to a human vascular targeting antibody in tandem diabody format [116].