The ectopic ACTH-secreting tumors were: pancreatic neuroendocrine tumor (n = 1), lung tumors [carcinoid (n = 1) and carcinoma (n = 1)], thymoma (n = 1), thymic carcinoma (n = 1), and pheochromocytoma (n = 1). This evidence concerns the gene POMC and pancreatic neuroendocrine tumor.