LIMK1 and congestive heart failure: To further investigate the effect of miR-93 targeting LIMK1 gene on plasma myocardial enzymes in rats with CHF, the results showed that in contrast to the miR-93 mimics + OE-NC group, LDH, AST, CK, and CK-MB levels in rat plasma were obviously increased in the miR-93 mimics + OE-LIMK1 group (all P < 0.05; Figure 6A–6D).