LIMK1 and congestive heart failure: To further investigate the effect of miR-93 targeting LIMK1 gene on echocardiography, hemodynamics and ventricular mass index in rats with CHF, the results of which showed that the levels of LVIDd, LVIDs, LVEDP, LVMI and RVMI in the miR-93 mimics + OE-LIMK1 group were significantly higher than those in the miR-93 mimics + OE-NC group, LVEF and LVFS, +dp/dt max and -dp/dt max levels were dramatically reduced (all P < 0.05; Figure 2A–2B).