In another study, Ismail et al 33 observed that homozygous GG genotype of the VDBP rs2282679 may be linked to asthma susceptibility and clinical findings in asthmatic patients including lung functions, asthma severity, and concentration of IgE and Vit D. In addition, Randolph et al 34 showed that carriers of C allele of the VDBP rs7041 had a higher risk to the progression of respiratory syncytial virus bronchiolitis and later asthma development (OR = 1.12, 95% CI = 1.02‐1.4, P = .03). This evidence concerns the gene IGHE and asthma.