Rho family GTPase (RND3, also known as RhoE), Cation transport regulator-like protein (CHAC1), and Immediate early response (IER3, also known as IEX1), which also induce apoptosis in glioblastoma cells48–50, were ranked in the top 10 (Fig. 4c). This evidence concerns the gene RND3 and glioblastoma.