Among the tumor-related genes, the top amplified genes included ERBB2 (17q21), MYC (8q24), GNAS (20q13), EGFR (7p11), ZNF217 (20q13), CCNE1(19q12), NCOA3 (20q13), and CDK6 (7q21), and the most frequently deleted genes were CDKN2A (9p21), CDKN2B (9p21), KIT (4q12), SMAD4 (18q21), and FGFR1 (8p12). Here, SMAD4 is linked to neoplasm.