In mouse Myc-CaP prostate carcinoma cells TW:E12 FDCs, but not TW homodimer FDCs, promote EMT phenotypes [30], while in hTERT immortalized human mammary epithelial cells (MECs) TW:E12 FDCs overcome RAS-induced senescence and promoted tumorigenesis compared with TW:TW FDCs [22]. The gene discussed is MYC; the disease is prostate carcinoma.