HLA-DRB1 and type 1 diabetes mellitus: First, although DQB1*02, DRB1*03, and DRB1*04 increase an individual’s susceptibility to both LADA and T1DM, while DQB1*05, DQB1*06, and DRB1*13 protect an individual from developing LADA and T1DM, these loci clearly have a stronger impact on T1DM than on LADA (e.g., DRB1*13: LADA: OR = 0.583; T1DM: OR = 0.300 [45]).