Furthermore, HIF-1α also impairs the tumor cell susceptibility to CTL-mediated killing by inducing the expression of microRNA (miR)-210, which targets the non-receptor protein tyrosine phosphatase type 1 (PTPN1), homeobox A1 (HOXA1), and tumor protein p53-inducible protein 11 (TP53I11) [64]. This evidence concerns the gene HOXA1 and neoplasm.